Invention Grant
- Patent Title: 1,3,4-oxadiazole and 1,3,4-thiadiazole β-lactamase inhibitors
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Application No.: US13853443Application Date: 2013-03-29
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Publication No.: US08933233B2Publication Date: 2015-01-13
- Inventor: Yu Gui Gu , Yong He , Ning Yin , Dylan C. Alexander , Jason B. Cross , Chester A. Metcalf, III
- Applicant: Cubist Pharmaceuticals, Inc.
- Applicant Address: US MA Lexington
- Assignee: Cubist Pharmaceuticals, Inc.
- Current Assignee: Cubist Pharmaceuticals, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Lathrop & Gage LLP
- Agent Brian C. Trinque
- Main IPC: C07D471/08
- IPC: C07D471/08 ; A61K31/546 ; A61K31/439 ; A61K31/545 ; A61K31/407 ; A61K45/06 ; A61K31/436 ; A61K31/427
Abstract:
β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.
Public/Granted literature
- US20130303504A1 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS Public/Granted day:2013-11-14
Information query
