A system performs methods for well and reservoir management for optimized production of fluids in a reservoir. The system includes a knowledge engine configured to receive a plurality of field inputs, process and analyze the field inputs, and provide a plurality of outputs for presentation to an operator. The system also includes a user data interface configured to display the plurality of data outputs. The plurality of field inputs comprises chemical sensing data and at least one of: temperature, pressure, flow rate and concentration of production components from one or more individual wells located within the reservoir, seismic surveys of the reservoir, permeability, geochemistry and lithology of rock formations, and geographic information system (GIS) data associated with the reservoir.