A method and system for providing instance information data of at least one instance. The method has the steps of generating a semantic representation of the instance on the basis of at least one instance data source, providing a semantic representation of a domain on the basis of at least one structured domain data source, performing an integration of the semantic instance and domain representations to provide an integrated semantic representation and deriving automatically instance information data from the provided integrated semantic representation. The method and system allow to provide efficiently instance information data of a wide range of instances with technical entities and persons, in a particular patients in different domains such as radiology or anatomy.