This invention relates to information science, and discloses a friend matching and meeting-up management system and its operation method. In this invention, a meeting check-in portion of the friend matching and meeting-up management system includes a meeting site portion and a meeting confirming portion. In the whole meeting check-in process, users utilize communicators to communicate with a system manager, and the system manager assists and manages the meeting process of the users expecting to meet after the object is determined. It has higher safety, helps ensure that users meet successfully, and saves a lot of people and material resources. In this invention, the check-in function is formed by combining positioning technology and information transmitting technology based on smart phones and mobile communication technology, or the Internet and wireless technology, which brings people together to meet in person, beyond the virtual world, breaks down barriers and narrows the distance between people.