A punch biopsy device is disclosed with an integrated tissue base cutting component. In an embodiment, the punch biopsy device includes a cutting blade with first and second arms operatively coupled to a handle. The punch biopsy device includes a prong flexible and integral to the cutting blade, the prong comprising top and lateral sharp edges configured to pierce and cut tissue, respectively. The prong is configured to be inserted into a body in a neutral position with the prong parallel with the first and second arms. The prong is configured to move to a position perpendicular to the first and second arms when the cutting blade is withdrawn to allow for the prong to catch and pierce the tissue. The prong is configured to cut the tissue while in the position perpendicular to the first and second arms when the cutting blade is rotated manually via the handle.