Invention Grant
![Pyrazolo[1,5-a]pyrimidines useful as JAK2 inhibitors](/docs/US/2015-01-20/US08937064B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrazolo[1,5-a]pyrimidines useful as JAK2 inhibitors
- Patent Title (中): 吡唑并[1,5-a]嘧啶可用作JAK2抑制剂
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Application No.: US12817785Application Date: 2010-06-17
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Publication No.: US08937064B2Publication Date: 2015-01-20
- Inventor: Mark Ledeboer , Valerie Marone , Michelle Stewart , David Messersmith , John Duffy , Gabriel Martinez Botella , Jon Come , Huai Gao , Albert Pierce , Francesco Salituro
- Applicant: Mark Ledeboer , Valerie Marone , Michelle Stewart , David Messersmith , John Duffy , Gabriel Martinez Botella , Jon Come , Huai Gao , Albert Pierce , Francesco Salituro
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Booyong S. Lim
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D415/00 ; C07D487/00 ; A01N43/90 ; C07D487/04
![Pyrazolo[1,5-a]pyrimidines useful as JAK2 inhibitors](/abs-image/US/2015/01/20/US08937064B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds of formula (I) useful as selective inhibitors of JAK2 kinase. The invention also provides pharmaceutical acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions or disorders. The invention also provides processes for preparing the compounds of the invention.
Public/Granted literature
- US20110118255A1 PYRAZOLO[1,5-a]PYRIMIDINES USEFUL AS JAK2 INHIBITORS Public/Granted day:2011-05-19
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