Invention Grant
US08937084B2 Nitrogen containing morphinan derivatives and the use thereof 有权
含氮吗啡喃衍生物及其用途

Nitrogen containing morphinan derivatives and the use thereof
Abstract:
The application is directed to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R3a, R4, Y, and Z are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
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