There is offered a driving circuit for an electrophoretic display device directed to avoiding a problem that clearing display on a display unit is not performed when the power supply is lost and a wrong display such as wrong time display is left unchanged. In the driving circuit for the electrophoretic display device, either a display clearing signal or a display retaining signal is set in a display setting register in advance. When the loss of the power supply is detected by a low voltage detection circuit while the display clearing signal is retained in the display setting register, the display on the display unit is cleared or retained in accordance with the setting in the display setting register.