Invention Grant
- Patent Title: Methods and compositions for altering photophysical properties of fluorophores via proximal quenching
- Patent Title (中): 通过近端淬火改变荧光团的光物理性质的方法和组合物
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Application No.: US13202351Application Date: 2010-02-19
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Publication No.: US08945515B2Publication Date: 2015-02-03
- Inventor: Scott Blanchard , Roger Altman , J. David Warren
- Applicant: Scott Blanchard , Roger Altman , J. David Warren
- Applicant Address: US NY Ithaca
- Assignee: Cornell University
- Current Assignee: Cornell University
- Current Assignee Address: US NY Ithaca
- Agency: Scully, Scott, Murphy & Presser, P.C.
- International Application: PCT/US2010/024824 WO 20100219
- International Announcement: WO2010/096720 WO 20100826
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61K49/00 ; G01N33/542
Abstract:
The invention is directed to fluorophore-containing compositions and configurations wherein proximity between the fluorophore and one or more protective agents (PAs) modifies the lifetime of fluorescent and/or dark states, their frequency of occurrence, and the total lifetime of fluorescence in order to appropriately modify the photophysical characteristics of the fluorophore. The invention is also directed to methods that utilize these compositions and configurations.
Public/Granted literature
- US20120027689A1 METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING Public/Granted day:2012-02-02
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