Invention Grant
US08945530B2 DNA sequence, and recombinant preparation of the grass pollen allergen Lol p4
有权
DNA序列，重组制备草花粉过敏原Lol p4
- Patent Title: DNA sequence, and recombinant preparation of the grass pollen allergen Lol p4
- Patent Title (中): DNA序列，重组制备草花粉过敏原Lol p4
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Application No.: US12961034Application Date: 2010-12-06
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Publication No.: US08945530B2Publication Date: 2015-02-03
- Inventor: Andreas Nandy , Helmut Fiebig , Oliver Cromwell
- Applicant: Andreas Nandy , Helmut Fiebig , Oliver Cromwell
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE10359352 20031216
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N1/12 ; C12N1/20 ; C12N15/00 ; C12N15/09 ; C12P21/04 ; C12P21/06 ; C07K14/415 ; A61K39/00
Abstract:
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.
Public/Granted literature
- US20110104209A1 DNA SEQUENCE, AND RECOMBINANT PREPARATION OF THE GRASS POLLEN ALLERGEN LOL P4 Public/Granted day:2011-05-05
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