Invention Grant
US08945559B2 Stabilized formulations containing anti-interleukin-4 receptor (IL-4R) antibodies
有权
含有抗白细胞介素-4受体（IL-4R）抗体的稳定制剂
- Patent Title: Stabilized formulations containing anti-interleukin-4 receptor (IL-4R) antibodies
- Patent Title (中): 含有抗白细胞介素-4受体（IL-4R）抗体的稳定制剂
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Application No.: US13253103Application Date: 2011-10-05
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Publication No.: US08945559B2Publication Date: 2015-02-03
- Inventor: Daniel B. Dix , Xiaolin Tang
- Applicant: Daniel B. Dix , Xiaolin Tang
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Alston & Bird LLP
- Agent Christopher Westberg; Aparna Patankar
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28
Abstract:
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
Public/Granted literature
- US20120097565A1 Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) Antibodies Public/Granted day:2012-04-26
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