Invention Grant
- Patent Title: Methods for improving the bioactivity of therapeutic IgE antibodies for the treatment of disease
- Patent Title (中): 改善治疗性IgE抗体生物活性以治疗疾病的方法
-
Application No.: US13456492Application Date: 2012-04-26
-
Publication No.: US08945566B2Publication Date: 2015-02-03
- Inventor: Birgit C. Schultes , Christopher F. Nicodemus
- Applicant: Birgit C. Schultes , Christopher F. Nicodemus
- Applicant Address: CA Alberta
- Assignee: Quest PharmaTech, Inc.
- Current Assignee: Quest PharmaTech, Inc.
- Current Assignee Address: CA Alberta
- Agency: Elmore Patent Law Group, P.C.
- Agent Darlene A. Vanstone; Carolyn S. Elmore, Esq.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00
Abstract:
The invention provides a method for increasing the bioactivity (e.g. the biosafety and efficacy) of a therapeutic IgE antibody of the invention in the treatment of a patient. Methods of the invention include: i) administering to the patient a therapeutic IgE antibody in combination with at least one bioactivity-enhancing agent, ii) strategic treatment regimens and protocols for the dosing and administration of a therapeutic IgE antibody of the invention, and iii) the use of a therapeutic IgE antibody having a variable region comprising at least one antigen binding region specific for binding an epitope of an antigen wherein the epitope is not highly repetitive or is non-repetitive.
Public/Granted literature
- US20130058920A1 METHODS FOR IMPROVING THE BIOACTIVITY OF THERAPEUTIC IgE ANTIBODIES FOR THE TREATMENT OF DISEASE Public/Granted day:2013-03-07
Information query
