Invention Grant
- Patent Title: Jagged-binding agents and uses thereof
- Patent Title (中): 锯齿结合剂及其用途
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Application No.: US13510666Application Date: 2010-11-19
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Publication No.: US08945569B2Publication Date: 2015-02-03
- Inventor: Austin L. Gurney , Timothy Charles Hoey , Aaron Ken Sato , Alexandra Lazetic , Zhimin Ji
- Applicant: Austin L. Gurney , Timothy Charles Hoey , Aaron Ken Sato , Alexandra Lazetic , Zhimin Ji
- Applicant Address: US CA Redwood City
- Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/US2010/057432 WO 20101119
- International Announcement: WO2011/063237 WO 20110526
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K16/28 ; A61K39/395 ; A61K39/00
Abstract:
Antibodies that specifically bind to an extracellular domain of human Jagged 1 or human Jagged2 and modulate Jagged activity, and methods of using said antibodies to inhibit tumor growth are disclosed. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an anti-Jagged antibody to a patient having a tumor or cancer.
Public/Granted literature
- US20120301489A1 Jagged-Binding Agents and Uses Thereof Public/Granted day:2012-11-29
Information query
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