Invention Grant
US08945578B2 Method of treating cancer with an HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
有权
用HLA-A * 3303限制性WT1肽治疗癌症的方法和包含其的药物组合物
- Patent Title: Method of treating cancer with an HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
- Patent Title (中): 用HLA-A * 3303限制性WT1肽治疗癌症的方法和包含其的药物组合物
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Application No.: US14145363Application Date: 2013-12-31
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Publication No.: US08945578B2Publication Date: 2015-02-03
- Inventor: Haruo Sugiyama
- Applicant: International Institute of Cancer Immunology, Inc.
- Applicant Address: JP Osaka
- Assignee: International Institute of Cancer Immunology, Inc.
- Current Assignee: International Institute of Cancer Immunology, Inc.
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: JP2006-045287 20060222
- Main IPC: C07K7/06
- IPC: C07K7/06 ; C07K14/47 ; C07K19/00 ; C12N15/09 ; C12N15/06 ; C12N15/11 ; C12N15/12 ; C12N15/63 ; C12N5/00 ; C12N5/02 ; C12N5/071 ; C12N5/0783 ; A61K38/08 ; G01N33/50 ; G01N33/574 ; A61K39/00 ; A61K38/00
Abstract:
Disclosed are: a peptide comprising an amino acid sequence composed of contiguous nine amino acid residues derived from a WT1 protein, wherein an amino acid residue at position 2 in the amino acid sequence is selected from the group consisting of Ala, Ile, Leu, Val, Phe, Tyr, Ser and Asp and an amino acid residue at position 9 in the amino acid sequence is Arg; a polynucleotide encoding the peptide; a pharmaceutical composition comprising the peptide; and a method of treating cancer using the peptide.
Public/Granted literature
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