Invention Grant
- Patent Title: Whole cell biocatalyst
- Patent Title (中): 全细胞生物催化剂
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Application No.: US13509935Application Date: 2010-11-16
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Publication No.: US08945887B2Publication Date: 2015-02-03
- Inventor: Joachim Jose , Ruth Maas , Christian Detzel
- Applicant: Joachim Jose , Ruth Maas , Christian Detzel
- Applicant Address: DE
- Assignee: Zyrus Beteiligungsgesellschaft mbH & Co. Patente I KG
- Current Assignee: Zyrus Beteiligungsgesellschaft mbH & Co. Patente I KG
- Current Assignee Address: DE
- Agency: Greenberg Traurig, LLP
- Priority: EP09014294 20091116
- International Application: PCT/EP2010/006951 WO 20101116
- International Announcement: WO2011/057820 WO 20110519
- Main IPC: C12N15/70
- IPC: C12N15/70 ; C12P7/42 ; C12N9/78
Abstract:
The present invention relates to a method for producing a product of a reaction catalysed by a nitrilase, which method comprises the steps (i) providing a microorganism comprising said nitrilase located on its surface, and/or a membrane preparation of said microorganism, and (ii) contacting the microorganism and/or the membrane preparation thereof with one or more nitrilase substrates under conditions compatible with nitrilase activity. The present invention further relates to a method for producing enantiomerically pure (R)-mandelic acid using the nitrilase-displaying whole cell biocatalyst or membrane preparation thereof for the conversion of racemic mandelonitrile.
Public/Granted literature
- US20130011890A1 WHOLE CELL BIOCATALYST Public/Granted day:2013-01-10
Information query
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