Invention Grant
US08945907B2 Genetically engineered recombinant Escherichia coli producing L-tryptophan having originally L-phenylalanine productivity, and method for producing L-tryptophan using the microorganism
有权
生产L-苯丙氨酸生产力的基因工程重组大肠杆菌生产L-色氨酸，以及使用该微生物生产L-色氨酸的方法
- Patent Title: Genetically engineered recombinant Escherichia coli producing L-tryptophan having originally L-phenylalanine productivity, and method for producing L-tryptophan using the microorganism
- Patent Title (中): 生产L-苯丙氨酸生产力的基因工程重组大肠杆菌生产L-色氨酸，以及使用该微生物生产L-色氨酸的方法
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Application No.: US12520350Application Date: 2007-12-28
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Publication No.: US08945907B2Publication Date: 2015-02-03
- Inventor: Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
- Applicant: Jae-yeong Ju , Hyang Choi , Eun-sung Koh , Ji-sun Lee , Jin-ho Lee , So-young Kim , Chang-hyun Jin , Young-hoon Park
- Applicant Address: KR Seoul
- Assignee: CJ Cheiljedang Corporation
- Current Assignee: CJ Cheiljedang Corporation
- Current Assignee Address: KR Seoul
- Agency: Swanson & Bratschun, L.L.C.
- Priority: KR10-2006-0137650 20061229
- International Application: PCT/KR2007/006933 WO 20071228
- International Announcement: WO2008/082179 WO 20080710
- Main IPC: C12P13/22
- IPC: C12P13/22 ; C12N9/88 ; C12N15/52
Abstract:
The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinant E. coli strain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) of E. coli having L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.
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