Invention Grant
US08946124B2 Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols
有权
取代的3-(联苯-3-基)-8,8-二氟-4-羟基-1-氮杂螺[4.5]癸-3-烯-2-酮用于治疗和卤素取代的螺环酮醇
- Patent Title: Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols
- Patent Title (中): 取代的3-(联苯-3-基)-8,8-二氟-4-羟基-1-氮杂螺[4.5]癸-3-烯-2-酮用于治疗和卤素取代的螺环酮醇
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Application No.: US14000147Application Date: 2012-02-14
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Publication No.: US08946124B2Publication Date: 2015-02-03
- Inventor: Thomas Bretschneider , Reiner Fischer , Stefan Lehr , Elmar Gatzweiler , Ulrich Görgens , Isolde Häuser-Hahn , Ines Heinemann , Arnd Voerste
- Applicant: Thomas Bretschneider , Reiner Fischer , Stefan Lehr , Elmar Gatzweiler , Ulrich Görgens , Isolde Häuser-Hahn , Ines Heinemann , Arnd Voerste
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GmbH
- Current Assignee: Bayer Intellectual Property GmbH
- Current Assignee Address: DE Monheim
- Agency: Miles and Stockbridge
- Priority: EP11154805 20110217; DE102011080405 20110804
- International Application: PCT/EP2012/052521 WO 20120214
- International Announcement: WO2012/110519 WO 20120823
- Main IPC: A01N43/08
- IPC: A01N43/08 ; A01N43/38 ; C07D209/54 ; C07D307/94 ; A61K31/403 ; A61K45/06 ; A01N43/12
![Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols](/abs-image/US/2015/02/03/US08946124B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to novel compounds of the formula (I) in which W, X, Y, Z, A, B, D and G have the meanings given above, to a plurality of processes and intermediates for their preparation, and to their use as pesticides and/or herbicides and/or fungicides. The invention also relates to selective herbicidal compositions comprising, firstly, the halogen-substituted spirocyclic ketoenols and, secondly, a crop plant compatibility-improving compound.The present invention furthermore relates to the boosting of the action of crop protection compositions comprising, in particular, halogen-substituted spirocyclic ketoenols, through the addition of ammonium salts or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for producing them and to their application in crop protection as pesticides and/or fungicides and/or for preventing unwanted plant growth.The invention also relates to substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones of the formula (Ia) for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumor disorders.
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