Invention Grant
- Patent Title: Signal sequence-independent pIX phage display
- Patent Title (中): 信号序列独立pIX噬菌体展示
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Application No.: US13201334Application Date: 2010-02-24
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Publication No.: US08946128B2Publication Date: 2015-02-03
- Inventor: Geir Åge Løset
- Applicant: Geir Åge Løset
- Applicant Address: NO Oslo
- Assignee: Nextera AS
- Current Assignee: Nextera AS
- Current Assignee Address: NO Oslo
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: DK20090666 20090528
- International Application: PCT/EP2010/052344 WO 20100224
- International Announcement: WO2010/097411 WO 20100902
- Main IPC: C40B40/08
- IPC: C40B40/08 ; C12N15/10
Abstract:
The present invention provides an alternative scaffold for peptides displayed on filamentous phages through novel fusion proteins primarily originating from pIX. Libraries of filamentous phages can be created from fusion proteins, and a phage display system comprising a phagemid and a helper phage is a part of the invention. An aspect of the invention is a kit containing a phage display system comprising a phagemid that contains a nucleic acid encoding the fusion protein of the invention and a helper phage.
Public/Granted literature
- US20110301064A1 SIGNAL SEQUENCE-INDEPENDENT PIX PHAGE DISPLAY Public/Granted day:2011-12-08
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