Invention Grant
- Patent Title: Cancer cell death inducing agent having effects of potentiating anticancer drug against anticancer-drug-resistant cancer
- Patent Title (中): 具有增强抗癌药物抗癌药物耐药性癌症作用的癌细胞死亡诱导剂
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Application No.: US12734488Application Date: 2008-11-05
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Publication No.: US08946173B2Publication Date: 2015-02-03
- Inventor: Hiromi Kumon , Yasutomo Nasu , Masami Watanabe , Yuji Kashiwakura , Kensuke Kawasaki
- Applicant: Hiromi Kumon , Yasutomo Nasu , Masami Watanabe , Yuji Kashiwakura , Kensuke Kawasaki
- Applicant Address: JP Okayama
- Assignee: Momotaro-Gene Inc.
- Current Assignee: Momotaro-Gene Inc.
- Current Assignee Address: JP Okayama
- Agency: Fitch, Even, Tabin & Flannery LLP
- Priority: JP2007-287373 20071105
- International Application: PCT/JP2008/070541 WO 20081105
- International Announcement: WO2009/060982 WO 20090514
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/00 ; C12N15/86 ; A61K31/713
Abstract:
The present invention provides a drug capable of causing cancer cells to restore anticancer drug sensitivity in cases in which cancer has acquired resistance to an anticancer drug and inducing cell death in cancer cells. The present invention specifically provides a cancer cell death inducing agent comprising REIC/Dkk-3 DNA as an active ingredient and having effects of potentiating an anticancer drug for cancer cells having anticancer drug resistance.
Public/Granted literature
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