Invention Grant
US08946181B2 Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8
有权
通过抑制天然反义转录物到IRF8来治疗干扰素调节因子8（IRF8）相关疾病
- Patent Title: Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8
- Patent Title (中): 通过抑制天然反义转录物到IRF8来治疗干扰素调节因子8（IRF8）相关疾病
-
Application No.: US13519529Application Date: 2011-01-04
-
Publication No.: US08946181B2Publication Date: 2015-02-03
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: Joseph Collard , Olga Khorkova Sherman
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- International Application: PCT/US2011/020069 WO 20110104
- International Announcement: WO2011/082409 WO 20110707
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7088
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Interferon Regulatory Factor 8 (IRF8), in particular, by targeting natural antisense polynucleotides of Interferon Regulatory Factor 8 (IRF8). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of IRF8.
Public/Granted literature
Information query
IPC分类:
