Invention Grant
- Patent Title: Medium-chain length fatty acids, salts and triglycerides in combination with gemcitabine for treatment of pancreatic cancer
- Patent Title (中): 中链长度脂肪酸，盐和甘油三酯与吉西他滨联合治疗胰腺癌
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Application No.: US12809380Application Date: 2008-12-18
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Publication No.: US08946190B2Publication Date: 2015-02-03
- Inventor: Lyne Gagnon , Lilianne Geerts , Christopher Penney
- Applicant: Lyne Gagnon , Lilianne Geerts , Christopher Penney
- Applicant Address: CA Mont-Royal, Quebec
- Assignee: Prometic Biosciences Inc.
- Current Assignee: Prometic Biosciences Inc.
- Current Assignee Address: CA Mont-Royal, Quebec
- Agency: Clark & Elbing LLP
- International Application: PCT/CA2008/002190 WO 20081218
- International Announcement: WO2009/076761 WO 20090625
- Main IPC: A61K31/7068
- IPC: A61K31/7068 ; A61K31/517 ; A61K31/23 ; A61K31/20 ; A61P35/00
Abstract:
The present invention relates to the use of medium-chain length fatty acids of formula I, triglycerides of formula 2 (wherein n=6-10), salts thereof, or mixtures thereof, in combination with gemcitabine and optionally erlotinib in the treatment of pancreatic cancer in human patients. Exemplary medium-chain length fatty acid/triglyceride compounds include capric acid, sodium caprate, tricaprin, lauric acid, sodium laurate, and trilaurin.
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