Invention Grant
US08946230B2 Aryl- and heteroaryl- nitrogen-heterocyclic compounds as PDE10 inhibitors
有权
芳基和杂芳基氮杂环化合物作为PDE10抑制剂
- Patent Title: Aryl- and heteroaryl- nitrogen-heterocyclic compounds as PDE10 inhibitors
- Patent Title (中): 芳基和杂芳基氮杂环化合物作为PDE10抑制剂
-
Application No.: US13103858Application Date: 2011-05-09
-
Publication No.: US08946230B2Publication Date: 2015-02-03
- Inventor: Jennifer R. Allen , Kristin L. Andrews , Michael J. Frohn , Paul E. Harrington , Alexander J. Pickrell , Robert M. Rzasa
- Applicant: Jennifer R. Allen , Kristin L. Andrews , Michael J. Frohn , Paul E. Harrington , Alexander J. Pickrell , Robert M. Rzasa
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/506 ; A61K31/4709 ; C07D471/04 ; C07D401/14 ; C07D403/14 ; C07D405/14

Abstract:
Aryl- and heteroaryl-nitrogen heterocyclic compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein m, p, q, R1, R2, R3, X1, X2, X3, Y1 and Y2 are defined herein; and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like.
Public/Granted literature
- US20110306590A1 ARYL- AND HETEROARYL- NITROGEN-HETEROCYCLIC COMPOUNDS AS PDE10 INHIBITORS Public/Granted day:2011-12-15
Information query
IPC分类: