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US08946230B2 Aryl- and heteroaryl- nitrogen-heterocyclic compounds as PDE10 inhibitors 有权
芳基和杂芳基氮杂环化合物作为PDE10抑制剂

Aryl- and heteroaryl- nitrogen-heterocyclic compounds as PDE10 inhibitors
Abstract:
Aryl- and heteroaryl-nitrogen heterocyclic compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein m, p, q, R1, R2, R3, X1, X2, X3, Y1 and Y2 are defined herein; and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like.
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