Invention Grant
![4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines](/docs/US/2015-02-03/US08946240B2/abs.jpg.600x600.jpg)
- Patent Title: 4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines
- Patent Title (中): 4-氨基-3-（咪唑基） - 吡唑并[3,4-D]嘧啶
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Application No.: US13692930Application Date: 2012-12-03
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Publication No.: US08946240B2Publication Date: 2015-02-03
- Inventor: Penglie Zhang , Yibin Zeng
- Applicant: ChemoCentryx, Inc.
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Kilpatrick Townsend & Stockton LLP
- Agent William B. Kezer
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D487/00 ; C07D487/04
![4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines](/abs-image/US/2015/02/03/US08946240B2/abs.jpg.150x150.jpg)
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 4-amino-3-imidazoyl-pyrazolo[3,4-d]pyrimidine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20130178623A1 4-AMINO-3-(IMIDAZOLYL)-PYRAZOLO[3,4-D]PYRIMIDINES Public/Granted day:2013-07-11
Information query
IPC分类:
