Invention Grant
US08946246B2 Synthetic rigidin analogues as anticancer agents, salts, solvates and prodrugs thereof, and method of producing same
有权
作为抗癌剂，其盐，溶剂化物和前体药物的合成嘧啶类似物及其制备方法
- Patent Title: Synthetic rigidin analogues as anticancer agents, salts, solvates and prodrugs thereof, and method of producing same
- Patent Title (中): 作为抗癌剂，其盐，溶剂化物和前体药物的合成嘧啶类似物及其制备方法
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Application No.: US13678987Application Date: 2012-11-16
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Publication No.: US08946246B2Publication Date: 2015-02-03
- Inventor: Igor V. Magedov , Snezna Rogelj , Liliya Vladlenovna Frolova , Alexander Vladimir Kornienko
- Applicant: New Mexico Technical Research Foundation
- Applicant Address: US NM Socorro
- Assignee: New Mexico Technical Research Foundation
- Current Assignee: New Mexico Technical Research Foundation
- Current Assignee Address: US NM Socorro
- Agent Jennifer S. Stachniak; Robert W. Becker
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; C07D487/00 ; C07D487/04
Abstract:
A compound having the Formula I as follows: wherein R1 and R2 are selected from hydrogen, aryl, fused aryl, heteroaryl, saturated carbocylclic, partially saturated carbocyclic, saturated heterocyclic, partially saturated heterocyclic, C1-10 alkyl, haloalkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl, heteroarylalkenyl, carbocycloalkyl, heterocycloalkyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, nitroalkyl, cyanoalkyl, acetamidoalkyl, and acyloxyalkyl. A process for the preparation thereof is also provided.
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