Invention Grant
US08946273B2 S-Triazolyl alpha-mercapto acetanilides as inhibitors of HIV reverse transcriptase
有权
S-三唑基α-巯基乙酰替苯胺作为HIV逆转录酶的抑制剂
- Patent Title: S-Triazolyl alpha-mercapto acetanilides as inhibitors of HIV reverse transcriptase
- Patent Title (中): S-三唑基α-巯基乙酰替苯胺作为HIV逆转录酶的抑制剂
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Application No.: US13081398Application Date: 2011-04-06
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Publication No.: US08946273B2Publication Date: 2015-02-03
- Inventor: Jean-Luc Girardet , Yung-Hyo Koh , Martha A. De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Woo-Hong Kim
- Applicant: Jean-Luc Girardet , Yung-Hyo Koh , Martha A. De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Woo-Hong Kim
- Applicant Address: US CA San Diego
- Assignee: Ardea Biosciences, Inc.
- Current Assignee: Ardea Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D209/08 ; C07D249/12 ; C07D249/14
Abstract:
A series of S-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where Q is CO2H, CONR2, SO3H, or SO2NR2. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
Public/Granted literature
- US20110190491A1 S-TRIAZOLE ALPHA- MERCAPTOACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE Public/Granted day:2011-08-04
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