Invention Grant
- Patent Title: Manassatin compounds and methods of making and using the same
- Patent Title (中): 马尼他化合物及其制备和使用方法
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Application No.: US13130237Application Date: 2009-11-19
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Publication No.: US08946289B2Publication Date: 2015-02-03
- Inventor: Jiyong Hong , Mark Dewhirst , Hyoungsu Kim , Amanda C. Kasper , Eui Jung Moon , Yongho Park , Ceshea M. Wooten
- Applicant: Jiyong Hong , Mark Dewhirst , Hyoungsu Kim , Amanda C. Kasper , Eui Jung Moon , Yongho Park , Ceshea M. Wooten
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2009/065194 WO 20091119
- International Announcement: WO2010/059858 WO 20100527
- Main IPC: C07D307/12
- IPC: C07D307/12 ; A61K31/341 ; A61K31/40 ; C07D407/12
Abstract:
Provided are manassantin compounds and methods of using the compounds. Provided are methods of treating a disease, the method comprising administering a compound according to Formula I. Further provided are pharmaceutical compositions comprising compounds according to Formula I. Also provided are methods of inhibiting HIF-1 in a cell, the methods comprising administering to the cell a compound according to Formula I.
Public/Granted literature
- US20110230540A1 MANASSATIN COMPOUNDS AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2011-09-22
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