Invention Grant
- Patent Title: Bladder cancer specific ligand peptides
- Patent Title (中): 膀胱癌特异性配体肽
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Application No.: US13497041Application Date: 2010-09-23
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Publication No.: US08946379B2Publication Date: 2015-02-03
- Inventor: Chong-xian Pan , Hongyong Zhang , Kit S. Lam , Olulanu H. Aina
- Applicant: Chong-xian Pan , Hongyong Zhang , Kit S. Lam , Olulanu H. Aina
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Jennifer L. Wahlsten
- International Application: PCT/US2010/050037 WO 20100923
- International Announcement: WO2011/038142 WO 20110331
- Main IPC: C07K5/00
- IPC: C07K5/00 ; G01N33/574 ; A61K47/48 ; A61K49/00 ; B82Y5/00 ; C07K7/06 ; A61K38/00
Abstract:
The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.
Public/Granted literature
- US20120230994A1 BLADDER CANCER SPECIFIC LIGAND PEPTIDES Public/Granted day:2012-09-13
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