Invention Grant
- Patent Title: Automated radiosynthesis
- Patent Title (中): 自动放射合成
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Application No.: US13394655Application Date: 2010-10-08
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Publication No.: US08946410B2Publication Date: 2015-02-03
- Inventor: John Woodcraft , L Clare Jones , Alessandra Gaeta , John William Trigg , Alexander Paul Jones , Stuart Plant , Alexander Jackson
- Applicant: John Woodcraft , L Clare Jones , Alessandra Gaeta , John William Trigg , Alexander Paul Jones , Stuart Plant , Alexander Jackson
- Applicant Address: GB Amersham, Buckinghamshire
- Assignee: GE Healthcare Limited
- Current Assignee: GE Healthcare Limited
- Current Assignee Address: GB Amersham, Buckinghamshire
- Priority: GB0917611.6 20091008
- International Application: PCT/EP2010/065077 WO 20101008
- International Announcement: WO2011/042529 WO 20110414
- Main IPC: C07D487/04
- IPC: C07D487/04
Abstract:
The present invention provides a method to obtain radiofluorinated compounds useful for in vivo imaging GABAA receptors. The method of the invention is high-yielding and may conveniently be carried out on an automated synthesizer such as Fastlab™. A further aspect of the invention is a cassette suitable for carrying out the automated method of synthesis of the invention. Novel precursor compounds useful in the method of the invention are also provided, as are a number of novel compounds obtained by the method of the invention.
Public/Granted literature
- US20120190843A1 AUTOMATED RADIOSYNTHESIS Public/Granted day:2012-07-26
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