Invention Grant
US08946416B2 Process for the synthesis of 5-(methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzeneamine 有权
合成5-(甲基-1H-咪唑-1-基)-3-(三氟甲基) - 苯胺的方法

  • Patent Title: Process for the synthesis of 5-(methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzeneamine
  • Patent Title (中): 合成5-(甲基-1H-咪唑-1-基)-3-(三氟甲基) - 苯胺的方法
  • Application No.: US13353434
    Application Date: 2012-01-19
  • Publication No.: US08946416B2
    Publication Date: 2015-02-03
  • Inventor: Wen-Chung ShiehJoseph McKenna
  • Applicant: Wen-Chung ShiehJoseph McKenna
  • Applicant Address: CH Basel
  • Assignee: Novartis AG
  • Current Assignee: Novartis AG
  • Current Assignee Address: CH Basel
  • Agent Michelle A. Han
  • Main IPC: C07D401/14
  • IPC: C07D401/14 C07D401/04
Process for the synthesis of 5-(methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzeneamine
Abstract:
The present invention provides a new method of making compounds of formula (I): wherein R1 is mono- or polysubstituted aryl; R2 is hydrogen, lower alkyl or aryl; and R4 is hydrogen, lower alkyl or halogen.
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