Invention Grant
US08946434B2 Dihydropyridin-2(1H)-one compound as S-nirtosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists
有权
二氢吡啶-2（1H） - 酮化合物，作为S-半胱氨酸谷胱甘肽还原酶抑制剂和神经激肽-3受体拮抗剂
- Patent Title: Dihydropyridin-2(1H)-one compound as S-nirtosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists
- Patent Title (中): 二氢吡啶-2（1H） - 酮化合物，作为S-半胱氨酸谷胱甘肽还原酶抑制剂和神经激肽-3受体拮抗剂
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Application No.: US13805626Application Date: 2011-07-08
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Publication No.: US08946434B2Publication Date: 2015-02-03
- Inventor: Xicheng Sun , Jian Qiu
- Applicant: Xicheng Sun , Jian Qiu
- Applicant Address: US CO Boulder
- Assignee: N30 Pharmaceuticals, Inc.
- Current Assignee: N30 Pharmaceuticals, Inc.
- Current Assignee Address: US CO Boulder
- Agency: Swanson & Bratschun, L.L.C.
- International Application: PCT/US2011/043374 WO 20110708
- International Announcement: WO2012/009227 WO 20120119
- Main IPC: C07D401/00
- IPC: C07D401/00 ; C07D419/00 ; C07D409/00 ; C07D411/00 ; C07D211/72 ; C07D211/84 ; C07D213/62 ; C07D213/78 ; A61K31/44 ; C07D409/14 ; C07D211/88 ; C07D401/04 ; C07D401/14 ; C07D211/86 ; C07D409/04
Abstract:
The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
Public/Granted literature
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