An inventory and anti-theft alarm tag system that has (1) one or more RFID tags and (2) a master database. The RFID tags can include an RFID transmitter and an RFID inlay having a unique item number encoded therein. The RFID transmitter allows communication between the RFID tags and the master database. The master database can compare information from the RFID tags with information stored in the master database to determine if the RFID tags are authentic and have been opened or closed a defined number of times indicated in the master database, and if not, a message can be sent for investigation.