A slot-line waveguide optical switch system and method are disclosed. An optical switch system can include a slot-line waveguide optical switch that includes a plurality of wall portions that are each formed from a high refractive-index material and that are arranged to form a channel portion comprising an electro-optic material interposed to extend between the plurality of wall portions. The channel portion can include an input channel to receive an input optical signal and plural output channels to receive the input optical signal from the input channel. A channel switching system can provide a voltage to an electrode coupled to a corresponding wall portion to change a relative refractive index in the output channels via the electro-optic material and thereby switch the input optical signal to one of the output channels.