A wireless device includes impedance determination and processing circuitry. The impedance determination circuitry determines load impedance at an output of at least one Radio Frequency (RF) power amplifier of the wireless device. The processing circuitry couples to the impedance determination circuitry and alters at least one operating parameter of the wireless device based upon the determined load impedance. Alteration of at least one operating parameter of the wireless device may include altering a gain of at least one transmit path component, altering a gain of at least one receive path component, altering tuning settings of at least one transmit path component, altering tuning settings of at least one receive path component, altering a rail voltage setting, altering baseband processing pre-distortion settings, altering baseband processing receive signal processing operations, altering antenna configuration settings, altering antenna tuning parameters, altering antenna diversity settings, and altering Multi Input Multi Output (MIMO) settings.