A packaging for a mattress consisting of a wrapping provided by a sheet of heat-sealing plastics, the wrapping comprising two rectangular portions, which are sized to cover the opposite faces of the mattress and have perimetric regions which are folded so as to cover the perimetric band of the mattress and have, along at least two mutually opposite and parallel sides of the mattress, subflaps which are folded outward and heat-sealed to each other, so as to form wings provided with slots adapted to act as handles.