Invention Grant
US08951514B2 Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
有权
他汀类和ω-3脂肪酸用于降低载脂蛋白B水平
- Patent Title: Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
- Patent Title (中): 他汀类和ω-3脂肪酸用于降低载脂蛋白B水平
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Application No.: US13584480Application Date: 2012-08-13
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Publication No.: US08951514B2Publication Date: 2015-02-10
- Inventor: George Jackowski , Rachelle MacSweeney , Nisar Shaikh , Jason Yantha , Valerie Schini-Kerth
- Applicant: George Jackowski , Rachelle MacSweeney , Nisar Shaikh , Jason Yantha , Valerie Schini-Kerth
- Applicant Address: CA Woodbridge, Ontario
- Assignee: Pivotal Therapeutics Inc.
- Current Assignee: Pivotal Therapeutics Inc.
- Current Assignee Address: CA Woodbridge, Ontario
- Agency: Ferris H. Lander, Inc.
- Main IPC: A61K31/202
- IPC: A61K31/202 ; A61K31/4155 ; A61K31/4412 ; A61K35/60 ; A61K35/34 ; A61K35/44 ; A61K31/22 ; A61K31/40 ; A61K45/06 ; A61K47/12 ; A61K31/366 ; A61K31/404 ; A61K31/4418 ; A61K31/47 ; A61K31/662
Abstract:
A composition and a method of treatment utilizing a combination of statins (or HMG-CoA reductase inhibitors), a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, with mixtures of an omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight including a combination of Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DPA) and Docosahexaenoic acid (DHA) in a weight ratio of EPA:DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA represent about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition are taught.
Public/Granted literature
- US20130079310A1 STATIN AND OMEGA 3 FATTY ACIDS FOR REDUCTION OF APOLIPOPROTEIN-B LEVELS Public/Granted day:2013-03-28
Information query
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