Invention Grant
US08951536B2 N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
有权
N-羟基脒基杂环作为吲哚胺2,3-双加氧酶的调节剂
- Patent Title: N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
- Patent Title (中): N-羟基脒基杂环作为吲哚胺2,3-双加氧酶的调节剂
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Application No.: US13780510Application Date: 2013-02-28
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Publication No.: US08951536B2Publication Date: 2015-02-10
- Inventor: Andrew P. Combs , Amy Takvorian , Wenyu Zhu , Richard B. Sparks
- Applicant: Incyte Corporation
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/541
- IPC: A61K31/541 ; A61K31/4245 ; A61K31/454 ; A61K31/496 ; A61K31/06 ; A61K31/4725 ; A61K31/5377 ; A61K31/433 ; A61K31/427 ; A61K31/4439 ; C07D271/08 ; C07D285/06 ; C07D413/06 ; C07D413/12 ; C07D413/14 ; C07D417/06 ; C07D417/12 ; A61K45/06
Abstract:
The present invention is directed to N-hydroxyamidino compounds which are modulators of indoleamine 2,3-dioxygenase (IDO), as well as pharmaceutical compositions thereof and methods of use thereof relating to the treatment of cancer and other diseases.
Public/Granted literature
- US20130177590A1 N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE Public/Granted day:2013-07-11
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