Invention Grant
US08951742B2 Assessing susceptibility to cardiac intervention, susceptibility to therapy for heart failure, risk of mortality or further cardiovascular events, and risk of subsequent pulmonary embolism in relevant patients based on determinations of GDF-15, natriuretic peptide, cardiac troponin or combinations thereof
有权
基于GDF-15，利钠肽，心肌肌钙蛋白或其组合的测定，评估对心脏干预的敏感性，心力衰竭治疗的易感性，死亡风险或其他心血管事件以及相关患者随后的肺栓塞风险
- Patent Title: Assessing susceptibility to cardiac intervention, susceptibility to therapy for heart failure, risk of mortality or further cardiovascular events, and risk of subsequent pulmonary embolism in relevant patients based on determinations of GDF-15, natriuretic peptide, cardiac troponin or combinations thereof
- Patent Title (中): 基于GDF-15，利钠肽，心肌肌钙蛋白或其组合的测定，评估对心脏干预的敏感性，心力衰竭治疗的易感性，死亡风险或其他心血管事件以及相关患者随后的肺栓塞风险
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Application No.: US12363932Application Date: 2009-02-02
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Publication No.: US08951742B2Publication Date: 2015-02-10
- Inventor: Kai C. Wollert , Tibor Kempf , Lars Wallentin , Helmut Drexler
- Applicant: Kai C. Wollert , Tibor Kempf , Lars Wallentin , Christa Marianne Drexler , Beatrice Drexler
- Applicant Address: DE Hannover
- Assignee: Medizinische Hochschule Hannover
- Current Assignee: Medizinische Hochschule Hannover
- Current Assignee Address: DE Hannover
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: EP06118464 20060804; EP06121413 20060928; EP07108854 20070524
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/68
Abstract:
The present invention relates to a method of identifying a subject being susceptible to a cardiac intervention based on the determination of GDF-15 in a sample of a subject in need of a cardiac intervention. Moreover, the present invention pertains to a method for predicting the risk of mortality or a further acute cardiovascular event for a subject suffering from a cardiovascular complication based on the determination of GDF-15 and a natriuretic peptide and/or a cardiac troponin in a sample the said subject. Also encompassed by the present invention are devices and kits for carrying out the aforementioned methods.
Public/Granted literature
- US20110065204A1 ASSESSING RISK OF CARDIAC INTERVENTION BASED ON GDF-15 Public/Granted day:2011-03-17
Information query
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