Invention Grant
US08951758B2 GH61 glycoside hydrolase protein variants and cofactors that enhance GH61 activity
有权
GH61糖苷水解酶蛋白变体和增强GH61活性的辅因子
- Patent Title: GH61 glycoside hydrolase protein variants and cofactors that enhance GH61 activity
- Patent Title (中): GH61糖苷水解酶蛋白变体和增强GH61活性的辅因子
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Application No.: US13592060Application Date: 2012-08-22
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Publication No.: US08951758B2Publication Date: 2015-02-10
- Inventor: Jie Yang , Xiyun Zhang , Jungjoo Yoon , Kripa Rao , John H. Grate , David Elgart , Dipnath Baidyaroy
- Applicant: Jie Yang , Xiyun Zhang , Jungjoo Yoon , Kripa Rao , John H. Grate , David Elgart , Dipnath Baidyaroy
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12P19/14
- IPC: C12P19/14 ; C12P7/40 ; C12P7/56 ; C12P19/00 ; C12P7/10 ; C12N9/30 ; C12N9/42
Abstract:
The present invention provides various GH61 protein variants comprising various amino acid substitutions. The GH61 protein variants have an improved ability to synergize with cellulase enzymes, thereby increasing the yield of fermentable sugars obtained by saccharification of biomass. In some embodiments, sugars obtained from saccharification are fermented to produce numerous end-products, including but not limited to alcohol.
Public/Granted literature
- US20130052698A1 GH61 GLYCOSIDE HYDROLASE PROTEIN VARIANTS AND COFACTORS THAT ENHANCE GH61 ACTIVITY Public/Granted day:2013-02-28
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