Invention Grant
US08951796B2 Methods and compositions for expanding and stabilizing natural regulatory T cells
有权
用于扩增和稳定天然调节性T细胞的方法和组合物
- Patent Title: Methods and compositions for expanding and stabilizing natural regulatory T cells
- Patent Title (中): 用于扩增和稳定天然调节性T细胞的方法和组合物
-
Application No.: US13642811Application Date: 2011-04-21
-
Publication No.: US08951796B2Publication Date: 2015-02-10
- Inventor: Song Guo Zheng , David A. Horwitz , Juhua Wong
- Applicant: Song Guo Zheng , David A. Horwitz , Juhua Wong
- Applicant Address: US CA Los Angeles
- Assignee: University of Southern California
- Current Assignee: University of Southern California
- Current Assignee Address: US CA Los Angeles
- Agency: Morgan, Lewis & Bockius LLP
- International Application: PCT/US2011/033484 WO 20110421
- International Announcement: WO2011/133808 WO 20111027
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; A61K35/12
Abstract:
The present invention is directed to methods and compositions for expanding and stabilizing the phenotype of natural regulatory T cells. In particular, the present invention provides methods and compositions for treating natural regulatory T cells that renders the cells resistant to factors present in the inflammatory milieu and stabilizes the suppressive properties of the cells.
Public/Granted literature
- US20130084269A1 Methods and Compositions for Expanding and Stabilizing Natural Regulatory T Cells Public/Granted day:2013-04-04
Information query
