Invention Grant
- Patent Title: Hydrogel tissue adhesive having reduced degradation time
- Patent Title (中): 水凝胶组织粘合剂具有降低的降解时间
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Application No.: US13263364Application Date: 2010-04-09
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Publication No.: US08951989B2Publication Date: 2015-02-10
- Inventor: Mark E. Wagman
- Applicant: Mark E. Wagman
- Applicant Address: US CA Berkeley
- Assignee: Actamax Surgical Materials, LLC
- Current Assignee: Actamax Surgical Materials, LLC
- Current Assignee Address: US CA Berkeley
- Agency: McCarter & English
- International Application: PCT/US2010/030474 WO 20100409
- International Announcement: WO2010/118284 WO 20101014
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/715 ; C08L5/08 ; C08L5/12 ; C08L71/02 ; A61K31/717 ; A61K31/718 ; A61K31/719 ; A61K31/721 ; A61L24/00 ; A61L24/04 ; A61L31/04 ; A61L31/14 ; C08L1/04 ; C08L3/10 ; C08L5/02

Abstract:
A hydrogel tissue adhesive having decreased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm polyether amine in the presence of an oligomer additive, which promotes the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, such as a hemostat sealant or to prevent undesired tissue-to-tissue adhesions resulting from trauma or surgery.
Public/Granted literature
- US20120035129A1 HYDROGEL TISSUE ADHESIVE HAVING REDUCED DEGRADATION TIME Public/Granted day:2012-02-09
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