Invention Grant
- Patent Title: PRMT1 inhibitors and uses thereof
- Patent Title (中): PRMT1抑制剂及其用途
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Application No.: US14212057Application Date: 2014-03-14
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Publication No.: US08952026B2Publication Date: 2015-02-10
- Inventor: Lorna Helen Mitchell , Gideon Shapiro , Richard Chesworth , Paula Ann Boriack-Sjodin , Oscar Miguel Moradei
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07D231/12
- IPC: C07D231/12 ; C07D401/12 ; C07D405/12 ; C07D403/12 ; A61K31/4155 ; A61K31/415 ; A61K31/4439 ; A61K31/506
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
Public/Granted literature
- US20140288140A1 PRMT1 INHIBITORS AND USES THEREOF Public/Granted day:2014-09-25
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