Invention Grant
- Patent Title: Modulators of sperm hypermobility and uses thereof
- Patent Title (中): 精子超动力调节剂及其用途
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Application No.: US13667310Application Date: 2012-11-02
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Publication No.: US08952041B2Publication Date: 2015-02-10
- Inventor: Jayhong A. Chong , Magdalene M. Moran
- Applicant: Hydra Biosciences, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Hydra Biosciences, Inc.
- Current Assignee: Hydra Biosciences, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi LLP
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/42 ; A61K31/38 ; C07D271/08 ; A61K31/4245 ; A61F6/04 ; C07D413/14
Abstract:
The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.
Public/Granted literature
- US20130123310A1 MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF Public/Granted day:2013-05-16
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