Invention Grant
- Patent Title: Antimycotic pharmaceutical composition
- Patent Title (中): 抗真菌药物组合物
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Application No.: US13389071Application Date: 2010-07-29
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Publication No.: US08952044B2Publication Date: 2015-02-10
- Inventor: Hirokazu Kobayashi , Nobuo Kubota
- Applicant: Hirokazu Kobayashi , Nobuo Kubota
- Applicant Address: JP Shinagawa-ku, Tokyo JP Chuo-ku, Tokyo
- Assignee: Pola Pharma Inc.,Nihon Nohyaku Co., Ltd.
- Current Assignee: Pola Pharma Inc.,Nihon Nohyaku Co., Ltd.
- Current Assignee Address: JP Shinagawa-ku, Tokyo JP Chuo-ku, Tokyo
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: JP2009-194835 20090825
- International Application: PCT/JP2010/063230 WO 20100729
- International Announcement: WO2011/024620 WO 20110303
- Main IPC: A01N43/10
- IPC: A01N43/10 ; A01N25/00 ; A61K31/4178 ; A61K9/00 ; A61K47/08

Abstract:
A pharmaceutical composition which comprises 1) a compound represented by the following general formula (1) and/or a salt thereof; and 2) a ketone such as methyl ethyl ketone. Preferably, the compound represented by the following general formula (1) is luliconazole, where R1═R2=a chlorine atom: where R1 and R2 each independently represents a hydrogen atom or a halogen atom, and at least one of R1 and R2 represents a halogen atom. The present invention provides a preparation excellent in solubilization stability for a compound represented by the general formula (1) and/or a salt thereof in low-temperature or high-temperature storage.
Public/Granted literature
- US20120149745A1 ANTIMYCOTIC PHARMACEUTICAL COMPOSITION Public/Granted day:2012-06-14
Information query
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