Invention Grant
- Patent Title: Methods for inhibiting drug degradation
- Patent Title (中): 抑制药物降解的方法
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Application No.: US12919012Application Date: 2009-02-23
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Publication No.: US08952056B2Publication Date: 2015-02-10
- Inventor: Michael Eissenstat , Dehui Duan , Sergi Gulnik , John W. Erickson
- Applicant: Michael Eissenstat , Dehui Duan , Sergi Gulnik , John W. Erickson
- Applicant Address: US MD Gaithersburg
- Assignee: Sequoia Pharmaceuticals, Inc.
- Current Assignee: Sequoia Pharmaceuticals, Inc.
- Current Assignee Address: US MD Gaithersburg
- Agency: Perkins Coie LLP
- International Application: PCT/US2009/034924 WO 20090223
- International Announcement: WO2009/105781 WO 20090827
- Main IPC: A61K31/343
- IPC: A61K31/343 ; C07D307/78 ; C07D307/79
Abstract:
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.
Public/Granted literature
- US20110098237A1 METHODS FOR INHIBITING DRUG DEGRADATION Public/Granted day:2011-04-28
Information query
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