Invention Grant
- Patent Title: Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
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Application No.: US13787437Application Date: 2013-03-06
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Publication No.: US08952062B2Publication Date: 2015-02-10
- Inventor: Harry Cook , Martha Hamilton , Douglas Danielson , Colette Goderstad , Dayton T. Reardan
- Applicant: Jazz Pharmaceuticals, Inc.
- Applicant Address: US CA Palo Alto
- Assignee: Jazz Pharmaceuticals, Inc.
- Current Assignee: Jazz Pharmaceuticals, Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: A01N37/00
- IPC: A01N37/00 ; A01N31/00 ; A61K31/19 ; A61K31/045 ; A61K9/00 ; A61K31/191 ; A61K47/02 ; A61K47/08 ; A61K47/12
Abstract:
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
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