Invention Grant
- Patent Title: Designer osteogenic proteins
- Patent Title (中): 设计师成骨蛋白
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Application No.: US13211755Application Date: 2011-08-17
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Publication No.: US08952131B2Publication Date: 2015-02-10
- Inventor: Stephen Berasi , Robert Vincent Martinez , Michael John Cain , John Wozney , Howard Seeherman , Z. Sean Juo , Valerie P. Calabro , Christopher Todd Brown
- Applicant: Stephen Berasi , Robert Vincent Martinez , Michael John Cain , John Wozney , Howard Seeherman , Z. Sean Juo , Valerie P. Calabro , Christopher Todd Brown
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agency: Kacvinsky Daisak Bluni PLLC
- Main IPC: C07K14/51
- IPC: C07K14/51 ; C07H21/04 ; A61K38/18 ; A61P19/08 ; A61K38/00
Abstract:
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
Public/Granted literature
- US20120046227A1 DESIGNER OSTEOGENIC PROTEINS Public/Granted day:2012-02-23
Information query
