Invention Grant
- Patent Title: Compositions and their uses directed to huntingtin
- Patent Title (中): 组合及其用于亨廷顿的用途
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Application No.: US13789368Application Date: 2013-03-07
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Publication No.: US08952145B2Publication Date: 2015-02-10
- Inventor: Susan M. Freier
- Applicant: Isis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Casimir Jones, S.C.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113
Abstract:
Disclosed herein are compounds, compositions and methods for modulating the expression of huntingtin in a cell, tissue or animal. Further provided are methods of slowing or preventing Huntington's Disease (HD) progression using an antisense compound targeted to huntingtin. Additionally provided are methods of delaying or preventing the onset of Huntington's Disease (HD) in an individual susceptible to Huntington's Disease (HD). Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
Public/Granted literature
- US20130281684A1 COMPOSITIONS AND THEIR USES DIRECTED TO HUNTINGTIN Public/Granted day:2013-10-24
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