Systems and methods are provided for adaptive linearization of an amplifier system having a plurality of heterogeneous amplifier paths. An amplifier system includes a plurality of amplifier paths, each configured to provide an amplified output signal from an input signal, and a signal combiner configured to combine the amplified output signals from the plurality of amplifier paths to provide a system output, such that the system output is a non-linear function of the amplified output signals. A monitoring system is configured to sample the system output and normalize the sampled output to a signal level associated with the input signal. A signal processing component is configured to characterize the amplifier paths via an iterative adaptive linearization process, such that the system output is linear with respect to the input signal.