In a flat panel display and a method of fabricating the same, the flat panel display includes a substrate having a pixel region and alignment mark regions. The alignment mark regions are disposed at opposite sides of the pixel region and along the pixel region. A unit pixel array is arranged on the pixel region in a matrix manner. The alignment mark regions have at least one pair of alignment marks disposed thereon in an opposing manner. The alignment mark pairs are located in correspondence with respective columns of the unit pixel array.