A serial communication system includes a controller, a channel interleaved multiplexed data bus coupled to the controller, and a transceiver coupled to the channel interleaved multiplexed data bus. The channel interleaved multiplexed data bus is arranged as a two dimensional array of time domain interleaved data channels on a backplane of the communication system, the two dimensional array being based on a number of channels available on the backplane and fixed pattern sequence of data transmitted on the backplane.